Dynamics of the 2001 UK foot and mouth epidemic: stochastic dispersal in a heterogeneous landscape.
نویسندگان
چکیده
Foot-and-mouth is one of the world's most economically important livestock diseases. We developed an individual farm-based stochastic model of the current UK epidemic. The fine grain of the epidemiological data reveals the infection dynamics at an unusually high spatiotemporal resolution. We show that the spatial distribution, size, and species composition of farms all influence the observed pattern and regional variability of outbreaks. The other key dynamical component is long-tailed stochastic dispersal of infection, combining frequent local movements with occasional long jumps. We assess the history and possible duration of the epidemic, the performance of control strategies, and general implications for disease dynamics in space and time.
منابع مشابه
Topographic determinants of foot and mouth disease transmission in the UK 2001 epidemic
BACKGROUND A key challenge for modelling infectious disease dynamics is to understand the spatial spread of infection in real landscapes. This ideally requires a parallel record of spatial epidemic spread and a detailed map of susceptible host density along with relevant transport links and geographical features. RESULTS Here we analyse the most detailed such data to date arising from the UK ...
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Most of the mathematical models that were developed to study the UK 2001 foot-and-mouth disease epidemic assumed that the infectiousness of infected premises was constant over their infectious periods. However, there is some controversy over whether this assumption is appropriate. Uncertainty about which farm infected which in 2001 means that the only method to determine if there were trends in...
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عنوان ژورنال:
- Science
دوره 294 5543 شماره
صفحات -
تاریخ انتشار 2001